Tg(CAG-lacZ,-Ptp4a2,-EGFP)11Zyz
Transgene Detail
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| Symbol: |
Tg(CAG-lacZ,-Ptp4a2,-EGFP)11Zyz |
| Name: |
transgene insertion 11, Zhong-Yin Zhang |
| MGI ID: |
MGI:6153150 |
| Synonyms: |
iZEG-PRL2 |
| Transgene: |
Tg(CAG-lacZ,-Ptp4a2,-EGFP)11Zyz Location: unknown
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| Alliance: |
Tg(CAG-lacZ,-Ptp4a2,-EGFP)11Zyz page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Tg(CAG-lacZ,-Ptp4a2,-EGFP)11Zyz expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Ptp4a2 (MGI:1277117) |
conditional: expressed only after removal of floxed lacZ-STOP cassette |
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Mutation details: Using the piZEG plasmid, a transgene construct comprising the following elements was inserted into the genome: a CAG promoter, a lacZ enzymatic reporter gene cassette with triple poly(A) signals flanked by loxP sites, the coding region from the cDNA of the murine Ptp4a2 gene, an IRES, the EGFP fluorescent reporter gene and a poly(A) signal. The CAG promoter drives the expression of the lacZ genes but not the inserted Ptp4a2 nor the EGFP gene. Only after removasl of the lacZ gene would these two genes be expressed.
(J:250112)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:250112 Bai Y, et al., Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis. Sci Rep. 2016 Sep 26;6:34211 |
| All: |
1 reference(s) |
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Analysis Tools
