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Gene Expression Data
Assay Details
Assay
Reference: J:118798 Fan B, et al., Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007 Mar 1;303(1):222-30
Assay type: RNA in situ
MGI Accession ID: MGI:6158927
Gene symbol: Prss8
Gene name: serine protease 8 (prostasin)
Probe: prostasin probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6C prostasin: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Strong Widespread 6C prostacin Broad expression throughout the labyrinth.
Specimen 6D prostasin +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: chorionic plate Present Regionally restricted 6D +/+ prostasin No expression in basal layer of chorioallantoic plate.
Specimen 6D prostasin +/+ (inset): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cytotrophoblast Present Regionally restricted 6D +/+ prostasin (inset) Expression in cuboidal trophoblasts - other than in basal layer.
TS15: syncytiotrophoblast Present 6D +/+ prostasin (inset) Expression in elongated syncytiotrophoblasts.
Specimen E9.5 +/+ not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present
Specimen 6D prostasin -/-: embryonic day 9.5; Spint1Gt(OST380474)Lex/Spint1Gt(OST380474)Lex (more )
Structure Level Pattern Image Note
TS15: trophectoderm Present Regionally restricted 6D -/- prostasin Authors report a similar expression pattern in mutant placenta.
Specimen 6E prostasin (embryo): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Absent 6E prostasin (embryo)
TS15: limb bud Absent 6E prostasin (embryo)
TS15: otocyst Absent 6E prostasin (embryo)
Specimen 6E prostasin ys: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac Present 6E prostasin ys
Specimen E9.5 -/- not shown: embryonic day 9.5; Spint1Gt(OST380474)Lex/Spint1Gt(OST380474)Lex (more )
Structure Level Pattern Image Note
TS15: yolk sac Present Authors state expression in yolk sac remained unchanged in mutant mice.
Specimen E10.5 +/+ not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: chorioallantoic placenta Present Regionally restricted Authors state expression in wild-type continued through E10.5 with an identical expression pattern as described for E9.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory