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Nfatc1em4(cre/ERT2)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Nfatc1em4(cre/ERT2)Bzsh
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; endonuclease-mediated mutation 4, Bin Zhou
MGI ID: MGI:6163791
Synonyms: Nfatc1-2A-CreER
Gene: Nfatc1  Location: Chr18:80649420-80756286 bp, - strand  Genetic Position: Chr18, 53.66 cM, cytoband E4
Alliance: Nfatc1em4(cre/ERT2)Bzsh page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Nfatc1em4(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: The line was generated by inserting a cDNA encoding Cre recombinase fused with a mutant form of estrogen receptor hormon-binding domaine C (ERT2) followed by an 2A peptide sequence into the 9th exon using the CRISPR/Cas9 technology. (J:262529)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nfatc1 (mouse)
Summary of all recombinase alleles driven by Nfatc1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfatc1 Mutation:  49 strains or lines available
References
Original:  J:262529 Zhang H, et al., Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. Cell Res. 2017 Sep;27(9):1157-1177
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory