Runx2tm1.1Ygao
Targeted Allele Detail
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| Symbol: |
Runx2tm1.1Ygao |
| Name: |
runt related transcription factor 2; targeted mutation 1.1, Yuguang Gao |
| MGI ID: |
MGI:6164654 |
| Synonyms: |
Runx2flox |
| Gene: |
Runx2 Location: Chr17:44806873-45125518 bp, - strand Genetic Position: Chr17, 21.33 cM
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| Alliance: |
Runx2tm1.1Ygao page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:262625
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 2 floxed.
(J:262625)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Runx2 Mutation: |
44 strains or lines available
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| Original: |
J:262625 Chu Q, et al., Ablation of Runx2 in Ameloblasts Suppresses Enamel Maturation in Tooth Development. Sci Rep. 2018 Jun 25;8(1):9594 |
| All: |
3 reference(s) |
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Analysis Tools
