Tg(Sox10-cre/ERT2)1Sout
Transgene Detail
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| Symbol: |
Tg(Sox10-cre/ERT2)1Sout |
| Name: |
transgene insertion 1, E Southard-Smith |
| MGI ID: |
MGI:6201041 |
| Synonyms: |
Sox10-CreERT2 |
| Transgene: |
Tg(Sox10-cre/ERT2)1Sout Location: unknown
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| Alliance: |
Tg(Sox10-cre/ERT2)1Sout page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Sox10-cre/ERT2)1Sout expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Sox10 (MGI:98358) |
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Mutation details: Using the BAC containing Sox10 regulatory regions, a Cre recombinase coding region fused with a mutated ligand-binding domain of the human estrogen receptor (ERT2) was inserted directly downstream of the transcription initiation site. LoxP sites in the BAC flanking arms were removed prior to microinjection. The Sox10 regulatory regions drive neural crest-specific expression of CreERT2 recombinase.
(J:299312)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Sox10
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:299312 Deal KK, et al., Sox10-cre BAC transgenes reveal temporal restriction of mesenchymal cranial neural crest and identify glandular Sox10 expression. Dev Biol. 2020;471:119-13 |
| All: |
1 reference(s) |
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Analysis Tools
