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Tg(Chrna5-cre)1Et
Transgene Detail
Summary
Symbol: Tg(Chrna5-cre)1Et
Name: transgene insertion 1, Eric E Turner
MGI ID: MGI:6201568
Transgene: Tg(Chrna5-cre)1Et  Location: unknown  
Alliance: Tg(Chrna5-cre)1Et page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Chrna5-cre)1Et expression driven by 1 gene
 
Mutation details: A cre-expression cassette, followed by a polyadenylation sequence, was inserted into BAC clone RP24-318N16 at the initiating ATG codon of the first coding exon of the Chrna5 gene so that cre expression is driven by the regulatory sequences of the BAC gene. This BAC clone generated by the Gene Expression Nervous System Atlas (GENSAT) Project was furtehr subcloned to include only Chrna5 and deleting Chrna3 and Chrna4 genes on opposit strand of the original BAC clone. The resulting BAC was used to generate three independent lines. Transgenic line 1 was used for expression analyses. (J:264332)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Chrna5 (mouse)
Summary of all recombinase alleles driven by Chrna5.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:264332 Morton G, et al., Chrna5-expressing neurons in the interpeduncular nucleus mediate aversion primed by prior stimulation or nicotine exposure. J Neurosci. 2018 Jun 28;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory