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Ntsr1tm1.1(cre)Giml
Targeted Allele Detail
Summary
Symbol: Ntsr1tm1.1(cre)Giml
Name: neurotensin receptor 1; targeted mutation 1.1, Gina M Leinninger
MGI ID: MGI:6202112
Synonyms: NtsR1deltaNEO-Cre, NtsR1Dev
Gene: Ntsr1  Location: Chr2:180141769-180186772 bp, + strand  Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
Alliance: Ntsr1tm1.1(cre)Giml page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:263745
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ntsr1tm1.1(cre)Giml expression driven by 1 gene
 
Mutation details: The targeting vector was generated by inserting an IRES-Cre between the stop codon and the polyadenylation site of the sequence encoding the 3' end of the mouse NtsR1 gene, with an frt-flanked NEO cassette placed upstream of the IRES-Cre. Correctly recombined ES clones via homologous recombination were expanded, and injected into mouse blastocystes to generate chimeric males. Mice were bred to a FlpO deleter line to remove neo cessette to make constitutive cre expression throughout life. (J:263745)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ntsr1 (mouse)
Summary of all recombinase alleles driven by Ntsr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ntsr1 Mutation:  31 strains or lines available
References
Original:  J:263745 Woodworth HL, et al., Identification of Neurotensin Receptor Expressing Cells in the Ventral Tegmental Area across the Lifespan. eNeuro. 2018 Jan-Feb;5(1):ENEURO.0191-17.2018
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory