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Gt(ROSA)26Sortm3(CAG-Vcre)Maito
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm3(CAG-Vcre)Maito
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Mamoru Ito
MGI ID: MGI:6202425
Synonyms: CAG-VCre KI
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm3(CAG-Vcre)Maito page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:263660
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6JJic
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gt(ROSA)26Sortm3(CAG-Vcre)Maito expression driven by 1 gene
 
Mutation detailsA construct containing the Vcre gene driven by the CAG promoter was inserted into the intron of the Gt(ROSA)26Sor locus via homologous recombination in Wit 9 ES cells. VCre/VloxP is a site-specific recombination system, which was derived from plasmid p0908 of Vibrio sp. VCre is a recombinase that recognizes its own specific target sites (VloxP). (J:263660)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
Notes
ES cell line = Wit 9 (C57BL/6JJic).
References
Original:  J:263660 Yoshimura Y, et al., Novel reporter and deleter mouse strains generated using VCre/VloxP and SCre/SloxP systems, and their system specificity in mice. Transgenic Res. 2018 Apr;27(2):193-201
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory