Gt(ROSA)26Sortm4(CAG-Scre)Maito
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm4(CAG-Scre)Maito |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Mamoru Ito |
MGI ID: |
MGI:6202431 |
Synonyms: |
CAG-SCre KI |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm4(CAG-Scre)Maito page
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Germline Transmission: |
Earliest citation of germline transmission:
J:263660
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Parent Cell Line: |
Other (see notes) (ES Cell)
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Strain of Origin: |
C57BL/6JJic
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm4(CAG-Scre)Maito expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
chicken |
CAG |
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Mutation details: A construct containing the Scre gene driven by the CAG promoter was inserted into the intron of the Gt(ROSA)26Sor locus via homologous recombination in Wit 9 ES cells. SCre/SloxP is a site-specific recombination system that was derived from plasmid 1 of Shewanella sp. ANA-3. SCre is a recombinase that recognizes its own specific target sites (SloxP).
(J:263660)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
993 strains or lines available
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ES cell line = Wit 9 (C57BL/6JJic).
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Original: |
J:263660 Yoshimura Y, et al., Novel reporter and deleter mouse strains generated using VCre/VloxP and SCre/SloxP systems, and their system specificity in mice. Transgenic Res. 2018 Apr;27(2):193-201 |
All: |
1 reference(s) |
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