Spry1tm1Ssan
Targeted Allele Detail
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Symbol: |
Spry1tm1Ssan |
Name: |
sprouty RTK signaling antagonist 1; targeted mutation 1, Shomyseh Sanjabi |
MGI ID: |
MGI:6209491 |
Synonyms: |
Spry1flx |
Gene: |
Spry1 Location: Chr3:37694096-37698747 bp, + strand Genetic Position: Chr3, 18.46 cM
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Alliance: |
Spry1tm1Ssan page
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Germline Transmission: |
Earliest citation of germline transmission:
J:265930
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: Exon 3 was flanked by a loxP site on one side and a loxP site flanked neomycin resistance gene cassette on the other. This creates a conditional-ready allele with exon 3 (containing the entire coding region) floxed. Please note, the correct exon is 3 not 2 as reported in Shehata HM, et al, PNAS 2018.
(J:265930)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Spry1 Mutation: |
15 strains or lines available
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Original: |
J:265930 Shehata HM, et al., Lack of Sprouty 1 and 2 enhances survival of effector CD8(+) T cells and yields more protective memory cells. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8939-E8947 |
All: |
1 reference(s) |
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