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Sall4tm1.1(EGFP/cre/ERT2)Ykawa
Targeted Allele Detail
Summary
Symbol: Sall4tm1.1(EGFP/cre/ERT2)Ykawa
Name: spalt like transcription factor 4; targeted mutation 1.1, Yasuhiko Kawakami
MGI ID: MGI:6257344
Synonyms: Sall4 GCE
Gene: Sall4  Location: Chr2:168590252-168609121 bp, - strand  Genetic Position: Chr2, 88.99 cM
Alliance: Sall4tm1.1(EGFP/cre/ERT2)Ykawa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:266804
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase, Reporter)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Sall4tm1.1(EGFP/cre/ERT2)Ykawa expression driven by 1 gene
 
Mutation details: Sall4 exon1 was replaced with the GFP-Cre-ERT2 cassette followed by an frt flanked neo cassette via homologous recombination. Resulting mice were bred with Flpo mouse line to eliminate the neo cassette. (J:101977, J:266804)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sall4 (mouse)
Summary of all recombinase alleles driven by Sall4.
 

Expression
In Mice Carrying this Mutation: 24 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sall4 Mutation:  145 strains or lines available
References
Original:  J:266804 Tahara N, et al., Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice. Sci Rep. 2018 Nov 6;8(1):16410
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
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