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Agtpbp1tm1.2Ics
Targeted Allele Detail
Summary
Symbol: Agtpbp1tm1.2Ics
Name: ATP/GTP binding protein 1; targeted mutation 1.2, Mouse Clinical Institute
MGI ID: MGI:6270378
Gene: Agtpbp1  Location: Chr13:59597348-59705184 bp, - strand  
Alliance: Agtpbp1tm1.2Ics page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:263824
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA loxP was inserted upstream of exon 20, and an FRT site, loxP site, neomycin cassette, FRT site, and loxP site were inserted downstream of exon 21. FLP-mediated recombination removed the neomycin cassette, leaving exons 20-21 floxed. Cre-mediated recombination deleted exons 20 and 21. (J:263824)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Agtpbp1 Mutation:  66 strains or lines available
References
Original:  J:263824 Munoz-Castaneda R, et al., Cytoskeleton stability is essential for the integrity of the cerebellum and its motor- and affective-related behaviors. Sci Rep. 2018 Feb 15;8(1):3072
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory