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Bcl2a1dtm1Tac
Targeted Allele Detail
Summary
Symbol: Bcl2a1dtm1Tac
Name: B cell leukemia/lymphoma 2 related protein A1d; targeted mutation 1, Taconic
MGI ID: MGI:6272375
Gene: Bcl2a1d  Location: Chr9:88605341-88613903 bp, - strand  Genetic Position: Chr9, 47.24 cM
Alliance: Bcl2a1dtm1Tac page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:258915
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: An approximately 2.5 kb region, including exon 1 and the upstream promoter, was replaced with an FRT site, puro cassette, lox5171 site and an FRT site. Targeting was done in ES cells carrying Bcl2a1atm1Tac (J:258915)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl2a1d Mutation:  15 strains or lines available
References
Original:  J:258915 Schenk RL, et al., Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment. Cell Death Differ. 2017 Mar;24(3):534-545
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory