B3glcttm1b(KOMP)Wtsi
Targeted Allele Detail
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| Symbol: |
B3glcttm1b(KOMP)Wtsi |
| Name: |
beta-3-glucosyltransferase; targeted mutation 1b, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:6274693 |
| Synonyms: |
B3glct-LacZ-delta4 |
| Gene: |
B3glct Location: Chr5:149601695-149686064 bp, + strand Genetic Position: Chr5, 89.18 cM
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| Alliance: |
B3glcttm1b(KOMP)Wtsi page
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| IMPC: |
B3glct gene page |
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| Germline Transmission: |
Earliest citation of germline transmission:
J:286130
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| Parent Cell Line: |
JM8A3.N1 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Project Collection: |
KOMP-CSD
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The L1L2_Bact_P cassette was inserted at position 149632305 of Chromosome 5 upstream of the critical exon 4 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 4 at position 149633181. The critical exon 4 is thus flanked by loxP sites. A null/knockout allele was created by cre recombinase expression in mice carrying the tm1a allele to remove the neo selection cassette and loxP-flanked critical exon 4. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:94077)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Original: |
J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015; |
| All: |
3 reference(s) |
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Analysis Tools
