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Xcr1tm1(icre)Ciphe
Targeted Allele Detail
Summary
Symbol: Xcr1tm1(icre)Ciphe
Name: chemokine (C motif) receptor 1; targeted mutation 1, Centre d'ImmunoPhenomique
MGI ID: MGI:6279765
Synonyms: Xcr1Cre, Xcr1tm1Ciphe
Gene: Xcr1  Location: Chr9:123681380-123691094 bp, - strand  Genetic Position: Chr9, 74.71 cM, cytoband F4
Alliance: Xcr1tm1(icre)Ciphe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:270869
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Xcr1tm1(icre)Ciphe expression driven by 1 gene
 
Mutation details: A cassette containing the internal ribosome entry site (IRES) followed by a gene encoding the codon-improved version of Cre recombinase were inserted into the 3' -UTR of the Xcr1 gene 34 bp after the stop codon. (J:270869)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Xcr1 (mouse)
Summary of all recombinase alleles driven by Xcr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xcr1 Mutation:  33 strains or lines available
References
Original:  J:270869 Mattiuz R, et al., Novel Cre-Expressing Mouse Strains Permitting to Selectively Track and Edit Type 1 Conventional Dendritic Cells Facilitate Disentangling Their Complexity in vivo. Front Immunol. 2018;9:2805
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory