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Clec4fem1(cre)Glass
Endonuclease-mediated Allele Detail
Summary
Symbol: Clec4fem1(cre)Glass
Name: C-type lectin domain family 4, member f; endonuclease-mediated mutation 1, Christopher Glass
MGI ID: MGI:6283832
Synonyms: Clec4f-cre-tdTomato
Gene: Clec4f  Location: Chr6:83621524-83633098 bp, - strand  Genetic Position: Chr6, 35.94 cM
Alliance: Clec4fem1(cre)Glass page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase, Reporter)
Mutation:    Insertion
 
Clec4fem1(cre)Glass expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing is used to insert an internal ribosome entry site (IRES) fused to a Cre recombinase sequence, a viral 2A oligopeptide (T2A) that mediates ribosomal skipping, and a tdTomato variant of red fluorescent protein (RFP) sequence into the 3'UTR of the gene. (J:279524)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Clec4f (mouse)
Summary of all recombinase alleles driven by Clec4f.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clec4f Mutation:  29 strains or lines available
References
Original:  J:279524 Sakai M, et al., Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity. Immunity. 2019 Sep 26;
All:  15 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory