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Nxph4em1(cre)Zak
Endonuclease-mediated Allele Detail
Summary
Symbol: Nxph4em1(cre)Zak
Name: neurexophilin 4; endonuclease-mediated mutation 1, Zachary Knight
MGI ID: MGI:6285704
Synonyms: Nxph4-2a-cre
Gene: Nxph4  Location: Chr10:127361342-127370428 bp, - strand  Genetic Position: Chr10, 74.51 cM
Alliance: Nxph4em1(cre)Zak page
Mutation
origin
Strain of Origin:  FVB/N
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Nxph4em1(cre)Zak expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 was used to insert T2A-Cre sequence immediately upstream of the endogenous Nxph4 stop codon. The mutation was created in FVB/N mice. (J:272756)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nxph4 (mouse)
Summary of all recombinase alleles driven by Nxph4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nxph4 Mutation:  25 strains or lines available
References
Original:  J:272756 Zimmerman CA, et al., A gut-to-brain signal of fluid osmolarity controls thirst satiation. Nature. 2019 Mar 27;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory