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Gene Expression Data
Assay Details
Assay
Reference: J:25961 Ono Y, et al., Developmental expression of APEX nuclease, a multifunctional DNA repair enzyme, in mouse brains. Brain Res Dev Brain Res. 1995 May 26;86(1-2):1-6
Assay type: RNA in situ
MGI Accession ID: MGI:6285911
Gene symbol: Apex1
Gene name: apurinic/apyrimidinic endonuclease 1
Probe: APEX probe1
Probe preparation: labelled with S35 DNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cerebellum ventricular layer Strong 1A
TS21: diencephalon ventricular layer Strong 1A
TS21: telencephalon ventricular layer Strong 1A
TS21: brainstem Strong Regionally restricted 1A High levels of expression in ventricular zone of brainstem.

Specimen 1B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cerebellum ventricular layer Strong 1B
TS23: telencephalon ventricular layer Strong 1B

Specimen 1C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: telencephalon Strong Regionally restricted 1C Intense expression in ventricular zone of telencephalon.
TS26: cerebellum external granule cell layer Strong 1C

Specimen 1D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: telencephalon Strong Regionally restricted 1D Intense expression in ventricular zone of telencephalon.
TS27: cerebellum external granule cell layer Strong 1D

Specimen 1E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: telencephalon Strong Regionally restricted 1E Intense expression in ventricular zone of telencephalon.
TS28: cerebellum external granule cell layer Strong 1E

Specimen 1F: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong 1F

Specimen 1G: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 1G Basal level of expression in most brain regions except for the hippocampal formation.

Specimen 2: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus granule cell layer Strong 2
TS28: hippocampus pyramidal cell layer Strong 2
TS28: corpus callosum Absent 2 No significant expression in white matter, such as corpus callosum and fimbria.
TS28: fimbria hippocampus Absent 2 No significant expression in white matter, such as corpus callosum and fimbria.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory