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Gene Expression Data
Assay Details
Assay
Reference: J:25961 Ono Y, et al., Developmental expression of APEX nuclease, a multifunctional DNA repair enzyme, in mouse brains. Brain Res Dev Brain Res. 1995 May 26;86(1-2):1-6
Assay type: Northern blot
MGI Accession ID: MGI:6285912
Gene symbol: Apex1
Gene name: apurinic/apyrimidinic endonuclease 1
Probe: APEX cDNA2
Probe preparation: labelled with P32 DNA
Visualized with: Autoradiography
Results Image: 3A
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
Parietal cortex E18 E18.0 (a) TS26: parietal cortex Strong 10 µg; total RNA C57BL/6J Not Specified
Parietal cortex P1 P1 TS27: parietal cortex Strong (b) 10 µg; total RNA C57BL/6J Not Specified
Parietal cortex P7 P7 TS28: parietal cortex Present (c) 10 µg; total RNA C57BL/6J Not Specified
Parietal cortex P14 P14 TS28: parietal cortex Weak (d) 10 µg; total RNA C57BL/6J Not Specified
Parietal cortex P21 P21 TS28: parietal cortex Weak (d) 10 µg; total RNA C57BL/6J Not Specified
Parietal cortex P140 P140 TS28: parietal cortex Weak (d) 10 µg; total RNA C57BL/6J Not Specified
Cerebellum E18 E18.0 (a) TS26: cerebellum Ambiguous 10 µg; total RNA C57BL/6J Not Specified
Cerebellum P1 P1 TS27: cerebellum Ambiguous 10 µg; total RNA C57BL/6J Not Specified
Cerebellum P7 P7 TS28: cerebellum Strong (e) 10 µg; total RNA C57BL/6J Not Specified
Cerebellum P14 P14 TS28: cerebellum Present (f) 10 µg; total RNA C57BL/6J Not Specified
Cerebellum P21 P21 TS28: cerebellum Weak (g) 10 µg; total RNA C57BL/6J Not Specified
Cerebellum P140 P140 TS28: cerebellum Weak (g) 10 µg; total RNA C57BL/6J Not Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Level of expression in parietal cortex at P1 almost the same as at E18.
(c) Expression decreased with postnatal development.
(d) Expression reached constant basal levels of expression at P14 to adulthood.
(e) Maximum levels in cerebellum at P7.
(f) Expression in cerebellum declined.
(g) Expression in cerebellum at basal levels at P21 to adulthood.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory