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Gene Expression Data
Assay Details
Assay
Reference: J:200762 Buttler K, et al., Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013 Sep 15;381(2):365-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6296750
Gene symbol: Lyve1
Gene name: lymphatic vessel endothelial hyaluronan receptor 1
Antibody: Anti-Lyve1
Detection system: Alexa Fluor 488
Results
Specimen 7A/C: embryonic day 18.5 (more )
Note: Triple labeled: red - Lyve1; green - CD13 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 7A , 7C Expression in dermis of dorsal thoracic region.
TS26: lymphatic vessel Present Regionally restricted 7C , 7A Co-expression with Pecam1 in numerous small lymphatics.
Specimen 7D/F: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Note: Triple labeled: red - Lyve1; green - CD13 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 7F , 7D Expression in dermis of dorsal thoracic region.
TS26: lymphatic vessel Present Regionally restricted 7D , 7F Co-expression with Pecam1 in huge, irregularly distributed lymphatics.
Specimen 8A: embryonic day 18.5; Wnt5atm1Amc/Wnt5a+ (more )
Note: Triple labeled: red - Lyve1; green - CD13 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 8A Expression in dermis of abdominal region.
TS26: lymphatic vessel Present Regionally restricted 8A Co-expression with Pecam1 in huge, irregularly distributed lymphatics.
Specimen 8B: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Note: Triple labeled: red - Lyve1; green - CD13 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 8B Expression in dermis of abdominal region.
TS26: lymphatic vessel Present Regionally restricted 8B Authors report lymphatics of homozygous mutant mice are larger, but fewer, and located more deeply in the dermis.
Specimen S4B: embryonic day 18.5; Wnt5atm1Amc/Wnt5a+ (more )
Note: Triple labeled: red - Lyve1; green - CD13 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted S4B
TS26: lymphatic vessel Present Regionally restricted S4B
Specimen S4C: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Note: Triple labeled: red - Lyve1; green - CD13 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted S4C Authors report no difference between heterozygous and homozygous mutant mice.
TS26: lymphatic vessel Present Regionally restricted S4C Authors report no difference between heterozygous and homozygous mutant mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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