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Gene Expression Data
Assay Details
Assay
Reference: J:218168 Lauing KL, et al., Aggrecan is required for growth plate cytoarchitecture and differentiation. Dev Biol. 2014 Dec 15;396(2):224-36
Assay type: RNA in situ
MGI Accession ID: MGI:6305113
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe39
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 4D
TS26: long bone epiphyseal plate resting zone Present Widespread 4D Authors report expression throughout resting zone.
TS26: long bone epiphyseal plate proliferative zone Strong Regionally restricted 4D Peak expression in late-proliferative/prehypertrophic chondrocytes.
TS26: long bone epiphyseal plate hypertrophic zone Weak 4D Abrupt decline in hypertrophic zone.
Specimen 4E: embryonic day 18.5; Acancmd-Bc/Acancmd-Bc (more )
Structure Level Pattern Image Note
TS26: long bone epiphyseal plate Present Patchy 4E Diffuse, patchy expression in growth plates, with indiscriminate regions of intense expression, adjacent to areas of very low Sox9 expression.
TS26: tibia Present Patchy 4E Diffuse, patchy expression in growth plates, with indiscriminate regions of intense expression, adjacent to areas of very low Sox9 expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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