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Crhr2tm1(cre)Lbrl
Targeted Allele Detail
Summary
Symbol: Crhr2tm1(cre)Lbrl
Name: corticotropin releasing hormone receptor 2; targeted mutation 1, Stephen Liberles
MGI ID: MGI:6306111
Gene: Crhr2  Location: Chr6:55067034-55110001 bp, - strand  Genetic Position: Chr6, 27.33 cM
Alliance: Crhr2tm1(cre)Lbrl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:298576
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Crhr2tm1(cre)Lbrl expression driven by 1 gene
 
Mutation details: A targeting construct was designed to insert an internal ribosomal entry site (IRES) and a Cre Recombinase with a polyadenylation signal, followed by a frt-flanked neomycin resistance (neo) cassette, downstream of the stop codon of the corticotropin releasing hormone receptor 2 (Crhr2) gene. (J:101977, J:298576)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Crhr2 (mouse)
Summary of all recombinase alleles driven by Crhr2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crhr2 Mutation:  35 strains or lines available
References
Original:  J:298576 Prescott SL, et al., An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents. Cell. 2020 Apr 30;181(3):574-589.e14
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory