Sox9 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:239525 Peskett E, et al., Analysis of the Fgfr2C342Y mouse model shows condensation defects due to misregulation of Sox9 expression in prechondrocytic mesenchyme. Biol Open. 2017 Feb 15;6(2):223-231
Assay type:	RNA in situ
MGI Accession ID:	MGI:6306859
Gene symbol:	Sox9
Gene name:	SRY (sex determining region Y)-box 9

Probe:	Sox9 probe41
Probe preparation:	Antisense RNA

Results

4C ©

Specimen 4C: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: basisphenoid pre-cartilage condensation	Present		4C
TS21: cartilage condensation	Present		4C
TS21: ear mesenchyme	Present	Regionally restricted	4C	Expression is in the tympanic bulla.

4D ©

Specimen 4D: embryonic day 13.5; Fgfr2^tm4Lni/Fgfr2^tm4Lni (more

)

Structure	Level	Pattern	Image	Note
TS21: basisphenoid pre-cartilage condensation	Present		4D	The expression domain is enlarged in this mutant.
TS21: cartilage condensation	Present		4D	The expression domain is enlarged in this mutant.
TS21: ear mesenchyme	Present	Regionally restricted	4D	The expression domain is enlarged in this mutant.

4G ©

Specimen 4G: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: respiratory system cartilage	Present	Regionally restricted	4G	Expression is in a segmented pattern.
TS21: trachea	Present	Regionally restricted	4G	Expression is in a segmented pattern.

4H ©

Specimen 4H: embryonic day 13.5; Fgfr2^tm4Lni/Fgfr2^tm4Lni (more

)

Structure	Level	Pattern	Image	Note
TS21: respiratory system cartilage	Present		4H	The expression domain in the trachea and cricoid is enlarged in this mutant.
TS21: trachea	Present		4H	The expression domain in the trachea and cricoid is enlarged in this mutant.

5A ©

Specimen 5A: embryonic day 14.5 (more

)

Structure	Level	Image	Note
TS22: cartilage condensation	Present	5A	Expression is at the outer edge of precartilaginous condensations of the trachea.
TS22: respiratory system cartilage	Present	5A	Expression is at the outer edge of precartilaginous condensations of the trachea.
TS22: trachea mesenchyme	Present	5A	Expression is at the outer edge of precartilaginous condensations of the trachea.

5B ©

Specimen 5B: embryonic day 14.5; Fgfr2^tm4Lni/Fgfr2^tm4Lni (more

)

Structure	Level	Pattern	Image	Note
TS22: cartilage condensation	Present	Regionally restricted	5B	Expression is throughout an unsegmented sheet with a distinct gap between the condensation and the epithelium of the trachea.
TS22: respiratory system cartilage	Present	Regionally restricted	5B	Expression is throughout an unsegmented sheet with a distinct gap between the condensation and the epithelium of the trachea.
TS22: trachea mesenchyme	Present	Regionally restricted	5B	Expression is throughout an unsegmented sheet with a distinct gap between the condensation and the epithelium of the trachea.

Specimen not shown E18.5: embryonic day 18.5; Fgfr2^tm4Lni/Fgfr2^tm4Lni (more

)

Structure	Level	Pattern	Image	Note
TS26: coronal suture	Absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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