Slc6a4<em1(flpo)Fuyu> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6316965)

Slc6a4^{em1(flpo)Fuyu}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Slc6a4^{em1(flpo)Fuyu}
Name:	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; endonuclease-mediated mutation 1, Fu Yu
MGI ID:	MGI:6316965
Gene:	Slc6a4 Location: Chr11:76889429-76923166 bp, + strand Genetic Position: Chr11, 46.18 cM
Alliance:	Slc6a4^{em1(flpo)Fuyu} page

Mutation
origin

Strain of Origin:

C57BL/6NCrl

Mutation
description

Allele Type:

Endonuclease-mediated (Recombinase)

Mutation:

Insertion

Slc6a4^{em1(flpo)Fuyu} expression driven by 1 gene

Mutation details: CRISPR/Cas9-system was used to introduce an internal ribosomal entry site (IRES) and a Flpo recombinase sequence downstream of the stop codon of the solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (Slc6a4) gene. (J:101977)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a4 (mouse) Summary of all recombinase alleles driven by Slc6a4. Alliance mouse Slc6a4 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Slc6a4 Mutation:	51 strains or lines available

References

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)

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