Gene Expression Data
Assay Details
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Assay
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Reference:
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J:84903
Bolcato-Bellemin AL, et al., Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6324341
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Gene symbol:
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Itgb1
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Gene name:
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integrin beta 1 (fibronectin receptor beta)
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Results
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Specimen
6B:
embryonic day 14.5
(more  )
Specimen
6B:
(close  )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: small intestine |
Present |
Regionally restricted |
6B
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Expression predominantly localized in mesenchymal compartment, segregated in 2 distinct regions: 4-5 mesenchymal cells located just beneath epithelial cells (future lamina propria) and inner presumptive muscle layer.
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| TS22: small intestine epithelium |
Weak |
Regionally restricted |
6B
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Lesser extent of expression at basolateral membrane of epithelial cells.
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Specimen
6E:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Lama5tm1Jhm/Lama5tm1Jhm
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: small intestine mesenchyme |
Weak |
Regionally restricted |
6E
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Slight decrease in expression, mostly at subepithelial basement membrane region, and in mesenchyme in vicinity of epithelium.
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Analysis Tools