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Scxtm1(cre)Shuk
Targeted Allele Detail
Summary
Symbol: Scxtm1(cre)Shuk
Name: scleraxis scleraxis bHLH transcription factor; targeted mutation 1, Chisa Shukunami
MGI ID: MGI:6330743
Synonyms: ScxCreNeo
Gene: Scx  Location: Chr15:76341652-76343658 bp, + strand  Genetic Position: Chr15, 35.92 cM
Alliance: Scxtm1(cre)Shuk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:274387
Parent Cell Line:  KY1.1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Scxtm1(cre)Shuk expression driven by 1 gene
 
Mutation details: The targeting vector was designed to inser Cre, along with a translational stop codon followed by FRT-flanked PGK-Neo cassette inframe after the ATG codon of Scx coding region to replace most of the Scx exon 1. (J:274387)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Scx (mouse)
Summary of all recombinase alleles driven by Scx.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scx Mutation:  15 strains or lines available
References
Original:  J:274387 Yoshimoto Y, et al., Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system. Sci Rep. 2017 Mar 22;7:45010
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory