Tg(Atoh1-flpo/ERT2)#Alj
Transgene Detail
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| Symbol: |
Tg(Atoh1-flpo/ERT2)#Alj |
| Name: |
transgene insertion, Alexandra L Joyner |
| MGI ID: |
MGI:6331265 |
| Synonyms: |
Atoh-FlpoER |
| Transgene: |
Tg(Atoh1-flpo/ERT2)#Alj Location: unknown
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| Alliance: |
Tg(Atoh1-flpo/ERT2)#Alj page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Atoh1-flpo/ERT2)#Alj expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Atoh1 (MGI:104654) |
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Mutation details: The transgene was designed with a 1.4 kb mouse Atoh1 3' enhancer (and a beta-globin minimal promoter) sequence upstream of an Flp sequence optimized for translation in mammalian cells (Flpo) joined to the ERT2 mutated estrogen receptor ligand-binding domain by the linker sequence from the Flpe/ERT2 cassette. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:272495)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Atoh1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:272495 Wojcinski A, et al., Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors. Neural Dev. 2019 Feb 14;14(1):4 |
| All: |
2 reference(s) |
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Analysis Tools
