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P2rx2tm1.1(cre)Ttc
Targeted Allele Detail
Summary
Symbol: P2rx2tm1.1(cre)Ttc
Name: purinergic receptor P2X, ligand-gated ion channel, 2; targeted mutation 1, Thomas E Taylor-Clark
MGI ID: MGI:6331316
Gene: P2rx2  Location: Chr5:110487678-110491078 bp, - strand  Genetic Position: Chr5, 53.49 cM
Alliance: P2rx2tm1.1(cre)Ttc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:290412
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
P2rx2tm1.1(cre)Ttc expression driven by 1 gene
 
Mutation details: The targeting vector using bacterial artificial chromosomes (BACs) clone RP23-333M22 and RP23-354O18 was constructed by inserting a 2A-Cre cassette to replace the TGA stop codon of the P2rx2 gene. The Neo cassette flanked by SDA (self-deletion anchor) sites were removed in the cell. The vector was transfected into the C57BL/6 ES cell to establish mouse line by homologous recombination. (J:290412)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: P2rx2 (mouse)
Summary of all recombinase alleles driven by P2rx2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any P2rx2 Mutation:  31 strains or lines available
References
Original:  J:290412 Kim SH, et al., Development of a mouse reporter strain for the purinergic P2X2 receptor. eNeuro. 2020 Jul 15;:ENEURO.0203-20.2020
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory