Tg(Elf5-cre/ERT2,-GFP)3Rcha
Transgene Detail
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Symbol: |
Tg(Elf5-cre/ERT2,-GFP)3Rcha |
Name: |
transgene insertion 3, Rumela Chakrabarti |
MGI ID: |
MGI:6343503 |
Synonyms: |
Elf5CreERT2-GFP |
Transgene: |
Tg(Elf5-cre/ERT2,-GFP)3Rcha Location: unknown
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Alliance: |
Tg(Elf5-cre/ERT2,-GFP)3Rcha page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Elf5-cre/ERT2,-GFP)3Rcha expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt by homologous recombination into BAC clone RP23-44A14. The Neo cassette flanked by Frt sites was deleted after FLP-mediated recombination. Six lines were generated and three lines with GFP expression in the mammary glands were kept for the initial screening. Line 3 shows weak GPF and was excluded from further analyses.
(J:277468)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Elf5
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:277468 Singh S, et al., A new Elf5(Cre) (ERT) (2-) (GFP) BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues. FEBS Lett. 2019 May;593(10):1030-1039 |
All: |
1 reference(s) |
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