Tg(Elf5-cre/ERT2,-GFP)5Rcha
Transgene Detail
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| Symbol: |
Tg(Elf5-cre/ERT2,-GFP)5Rcha |
| Name: |
transgene insertion 5, Rumela Chakrabarti |
| MGI ID: |
MGI:6343505 |
| Synonyms: |
Elf5CreERT2-GFP |
| Transgene: |
Tg(Elf5-cre/ERT2,-GFP)5Rcha Location: unknown
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| Alliance: |
Tg(Elf5-cre/ERT2,-GFP)5Rcha page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Elf5-cre/ERT2,-GFP)5Rcha expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt by homologous recombination into BAC clone RP23-44A14. The Neo cassette flanked by Frt sites was deleted after FLP-mediated recombination. Six lines were generated and three lines with GFP expression in the mammary glands were kept for the initial screening. Line 2 and 5 showed strong GPF and essentially identical cre activity after tamoxifen induction. Line 2, male founder was selected for the detailed analysis.
(J:277468)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Elf5
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:277468 Singh S, et al., A new Elf5(Cre) (ERT) (2-) (GFP) BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues. FEBS Lett. 2019 May;593(10):1030-1039 |
| All: |
1 reference(s) |
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Analysis Tools
