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Rln3tm1.1(cre/GFP)Et
Targeted Allele Detail
Summary
Symbol: Rln3tm1.1(cre/GFP)Et
Name: relaxin 3; targeted mutation 1.1, Eric Turner
MGI ID: MGI:6356529
Gene: Rln3  Location: Chr8:84769696-84771608 bp, - strand  Genetic Position: Chr8, 40.26 cM
Alliance: Rln3tm1.1(cre/GFP)Et page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:302432
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Rln3tm1.1(cre/GFP)Et expression driven by 1 gene
 
Mutation details: The targeting vector contained, from 5' to 3', an internal ribosome entry site sequence (IRES), a Cre/GFP fusion protein sequence and a frt-flanked neo cassette inserted into the 3'UTR in exon 2 of the relaxin 3 gene (Rln3) on chromosome 8. Chimeric mice were bred to FLPe mice for removal of the neo cassette. (J:302432)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Rln3 (mouse)
Summary of all recombinase alleles driven by Rln3.
 

Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rln3 Mutation:  5 strains or lines available
References
Original:  J:302432 Nasirova N, et al., Mapping Cell Types and Efferent Pathways in the Ascending Relaxin-3 System of the Nucleus Incertus. eNeuro. 2020 Nov/Dec;7(6):ENEURO.0272-20.2020
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory