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Neurog3tm3.1(Ncre,Neurog3)Ggu
Targeted Allele Detail
Summary
Symbol: Neurog3tm3.1(Ncre,Neurog3)Ggu
Name: neurogenin 3; targeted mutation 3.1, Guoqiang Gu
MGI ID: MGI:6357881
Synonyms: Neurog3nCre
Gene: Neurog3  Location: Chr10:61968869-61970542 bp, + strand  Genetic Position: Chr10, 32.35 cM, cytoband B4
Alliance: Neurog3tm3.1(Ncre,Neurog3)Ggu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:272578
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Neurog3tm3.1(Ncre,Neurog3)Ggu expression driven by 1 gene
 
Mutation details: A targeting vector was constructed to contain Lox71, nCre-T2A-Neurog3, FRT flanked hygromycin cassette, Lox2272, Neurog3 polyA signal. Chimeras were crossed with Flpe mice to delete the FRT-flanked selection cassette. (J:272578)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Neurog3 (mouse)
Summary of all recombinase alleles driven by Neurog3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neurog3 Mutation:  19 strains or lines available
References
Original:  J:272578 Liu J, et al., Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory