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Angpt4tm1.1(cre)Ekl
Targeted Allele Detail
Summary
Symbol: Angpt4tm1.1(cre)Ekl
Name: angiopoietin 4; targeted mutation 1.1, Lauri Eklund
MGI ID: MGI:6357966
Gene: Angpt4  Location: Chr2:151753130-151787257 bp, + strand  Genetic Position: Chr2, 74.83 cM
Alliance: Angpt4tm1.1(cre)Ekl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:267502
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Angpt4tm1.1(cre)Ekl expression driven by 1 gene
 
Mutation details: Using recombineering approach, targeting vector contained 1.2 and 11.4 kb genomic arms and Cre-pA-Frt-Neo-pA-Frt cassette inserted into the first exon of the Angpt4 gene was used in homologous recombination in ES cells. An Frt-flanked Neo cassette was removed by crossing with the ACTB-FLPe transgenic mouse line. (J:267502)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Angpt4 (mouse)
Summary of all recombinase alleles driven by Angpt4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angpt4 Mutation:  30 strains or lines available
References
Original:  J:267502 Elamaa H, et al., Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina. Elife. 2018 Nov 16;7:e37776
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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07/02/2024
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