Kcnj8tm1.1Geno
Targeted Allele Detail
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| Symbol: |
Kcnj8tm1.1Geno |
| Name: |
potassium inwardly-rectifying channel, subfamily J, member 8; targeted mutation 1.1, Genoway |
| MGI ID: |
MGI:6358100 |
| Synonyms: |
Kir6.1flx |
| Gene: |
Kcnj8 Location: Chr6:142510563-142517340 bp, - strand Genetic Position: Chr6, 74.31 cM
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| Alliance: |
Kcnj8tm1.1Geno page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:277504
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| Parent Cell Line: |
E14TG2a (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: A loxP site together with an frt-flanked neomycin selection cassette was inserted in intron 1. Exon 2 contains the ATG translation initiation codon. A second loxP site was inserted distal to exon 2 in intron 2. The frt-flanked neomycin selection cassette was removed via FLP-mediated recombination.
(J:277504)
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| Original: |
J:277504 Aziz Q, et al., The ATP-sensitive potassium channel subunit, Kir6.1, in vascular smooth muscle plays a major role in blood pressure control. Hypertension. 2014 Sep;64(3):523-9 |
| All: |
6 reference(s) |
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Analysis Tools
