Gene Expression Data
Assay Details
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Assay
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Reference:
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J:26845
Fong GH, et al., Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 1995 Jul 6;376(6535):66-70
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6358139
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Gene symbol:
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Flt1
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Gene name:
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FMS-like tyrosine kinase 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2a:
embryonic day 8.5; Flt1tm1Jrt/Flt1 +
(more  )
Note: 8-10 somite stage
Specimen
2a:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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Note:
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8-10 somite stage
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Specimen
2b:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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Note:
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8-10 somite stage
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: yolk sac |
Present |
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2b
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Expression in yolk sacs lacking obvious vascular structures.
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Specimen
2c:
embryonic day 8.5; Flt1tm1Jrt/Flt1 +
(more )
Note: 8-10 somite stage
Specimen
2c:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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Note:
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8-10 somite stage
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: yolk sac blood vessel |
Present |
Regionally restricted |
2c
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Expression in endothelial cells lining vascular lumen.
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Specimen
2d:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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Note:
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8-10 somite stage
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: yolk sac |
Present |
Regionally restricted |
2d
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Expression in cells with elongated endothelial morphology found in lining of lumen and within cavities, and also lined up to form extensive endothelial sheets.
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Specimen
2i:
embryonic day 8.0; Flt1tm1Jrt/Flt1 +
(more )
Note: Early head-fold stage
Specimen
2i:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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Note:
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Early head-fold stage
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: yolk sac |
Present |
Regionally restricted |
2i
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Expression in angioblasts located either at periphery of blood island or at boder between adjacent blood islands.
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Specimen
2j:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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Note:
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Early head-fold stage
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: yolk sac |
Present |
Regionally restricted |
2j
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Expression in angioblasts frequently mixed with haematopoietic cells in interior of blood islands.
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Specimen
3a:
embryonic day 8.0; Flt1tm1Jrt/Flt1 +
(more )
Specimen
3a:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: cardiovascular system |
Present |
Regionally restricted |
3a
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In head-fold region, expression in microcapillaries.
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Specimen
3b:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: cardiovascular system |
Present |
Regionally restricted |
3b
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In head-fold region, expression in endothelial cells lining a large lumen.
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Specimen
3c:
embryonic day 8.5; Flt1tm1Jrt/Flt1 +
(more )
Note: 8-10 somite stage
Specimen
3c:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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Note:
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8-10 somite stage
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Specimen
3d:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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Note:
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8-10 somite stage
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Specimen
3e:
embryonic day 8.5; Flt1tm1Jrt/Flt1 +
(more )
Note: 8-10 somite stage
Specimen
3e:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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Note:
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8-10 somite stage
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Specimen
3f:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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Note:
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8-10 somite stage
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: dorsal aorta |
Present |
Regionally restricted |
3f
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Authors report expression in endothelial cells inside the aortic lumen.
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Specimen
3g:
embryonic day 8.5; Flt1tm1Jrt/Flt1 +
(more )
Specimen
3g:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: primitive ventricle endocardial tube |
Present |
Regionally restricted |
3g
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Authors report expression in endothelial cells inside the aortic lumen. Expression in endocardial cells lining the walls of the forming heart venticle.
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Specimen
3h:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Flt1tm1Jrt/Flt1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Glutaraldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: primitive ventricle |
Present |
Regionally restricted |
3h
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Expression in extra endothelial cells filling up the ventricular cavity.
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Analysis Tools
