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Cdh2tm1(cre/ERT)Linli
Targeted Allele Detail
Summary
Symbol: Cdh2tm1(cre/ERT)Linli
Name: cadherin 2; targeted mutation 1, Linheng Li
MGI ID: MGI:6359739
Synonyms: N-cad-CreERT
Gene: Cdh2  Location: Chr18:16721934-16942303 bp, - strand  Genetic Position: Chr18, 10.1 cM
Alliance: Cdh2tm1(cre/ERT)Linli page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:278627
Parent Cell Line:  GermLine mESC C57BL6/129SvJ, ASE-9005 (ES Cell)
Strain of Origin:  (C57BL/6 x 129X1/SvJ)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cdh2tm1(cre/ERT)Linli expression driven by 1 gene
 
Mutation details: A targeting vector containing cre/ERT-IRES-mCherry-BGH polyA-FRT-Neo-FRT is inserted into exon 1 of the gene, replacing endogenous start codon. MCherry expression cannot detected by direct fluorescence or by antibodies. (J:278627)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh2 (mouse)
Summary of all recombinase alleles driven by Cdh2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdh2 Mutation:  50 strains or lines available
References
Original:  J:278627 Zhao M, et al., N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells. Cell Rep. 2019 Jan 15;26(3):652-669.e6
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory