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Mir140em2Asah
Endonuclease-mediated Allele Detail
Summary
Symbol: Mir140em2Asah
Name: microRNA 140; endonuclease-mediated mutation 2, Hiroshi Asahara
MGI ID: MGI:6359824
Synonyms: miR-140132del
Gene: Mir140  Location: Chr8:108277876-108277945 bp, + strand  Genetic Position: Chr8, 54.33 cM
Alliance: Mir140em2Asah page
Mutation
origin
Strain of Origin:  (C57BL/6J x DBA)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR-targeted of exon 2 resulted in a 132 nucleotide deletion and a frameshift premature termination. (J:278573)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir140 Mutation:  3 strains or lines available
Notes
Generated in conjunction with Wwp2em2Asah.
References
Original:  J:278573 Inui M, et al., Dissecting the roles of miR-140 and its host gene. Nat Cell Biol. 2018 May;20(5):516-518
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory