Mir140<em2Asah> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6359824)

Mir140^em2Asah
Endonuclease-mediated Allele Detail

Summary

Symbol:	Mir140^em2Asah
Name:	microRNA 140; endonuclease-mediated mutation 2, Hiroshi Asahara
MGI ID:	MGI:6359824
Synonyms:	miR-140^132del
Gene:	Mir140 Location: Chr8:108277876-108277945 bp, + strand Genetic Position: Chr8, 54.33 cM
Alliance:	Mir140^em2Asah page

Mutation
origin

Strain of Origin:

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Intragenic deletion
		Mutation details: CRISPR-targeted of exon 2 resulted in a 132 nucleotide deletion and a frameshift premature termination. (J:278573)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Mir140 Mutation:	3 strains or lines available

Notes

Generated in conjunction with Wwp2^em2Asah.

References

Original:	J:278573 Inui M, et al., Dissecting the roles of miR-140 and its host gene. Nat Cell Biol. 2018 May;20(5):516-518
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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