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Slc6a4tm1.1(flpo)Luo
Targeted Allele Detail
Summary
Symbol: Slc6a4tm1.1(flpo)Luo
Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; targeted mutation 1.1, Liqun Luo
MGI ID: MGI:6360133
Gene: Slc6a4  Location: Chr11:76889429-76923166 bp, + strand  Genetic Position: Chr11, 46.18 cM
Alliance: Slc6a4tm1.1(flpo)Luo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac x C57BL/6J
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Slc6a4tm1.1(flpo)Luo expression driven by 1 gene
 
Mutation details: An IRES-FlpO-loxP2272-ACE-Cre POII NeoR-loxp2272 cassette was inserted after the TAA stop codon of Slc6a4/Sert via homologous recombination in embryonic stem (ES) cells. The loxP2272-ACE-Cre POII NeoR-loxp2272 portion of the mutation is self-excised. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc6a4 (mouse)
Summary of all recombinase alleles driven by Slc6a4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc6a4 Mutation:  53 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory