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Tg(Amelx-icre)876Ppap
Transgene Detail
Summary
Symbol: Tg(Amelx-icre)876Ppap
Name: transgene insertion 876, Petros Papagerakis
MGI ID: MGI:6360640
Synonyms: Amelx-iCre(876)
Transgene: Tg(Amelx-icre)876Ppap  Location: unknown  
Alliance: Tg(Amelx-icre)876Ppap page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Amelx-icre)876Ppap expression driven by 1 gene
 
Mutation details: The transgene was created by modifying BAC by replacing exon 2 of mouse Amelx gene with an improved cre recombinase gene (icre). An FRT-flanked kanomycin resistance cassette was removed prior to injection. 4 independent BAC founder lines (854, 863, 872, and 876) were collected. Line 876 showed the strongest X-gal staining in ameloblasts. However, non-specific staining in the osteoclasts and osteoblasts are noted. (J:278625)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Amelx (mouse)
Summary of all recombinase alleles driven by Amelx.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:278625 Said R, et al., Generation of Amelx-iCre Mice Supports Ameloblast-Specific Role for Stim1. J Dent Res. 2019 Aug;98(9):1002-1010
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory