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Mfsd2aem2(cre/ERT2)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Mfsd2aem2(cre/ERT2)Bzsh
Name: MFSD2 lysolipid transporter A, lysophospholipid; endonuclease-mediated mutation 2, Bin Zhou
MGI ID: MGI:6361460
Synonyms: Mfsd2a-CrexER
Gene: Mfsd2a  Location: Chr4:122840643-122854981 bp, - strand  Genetic Position: Chr4, 57.34 cM, cytoband D1
Alliance: Mfsd2aem2(cre/ERT2)Bzsh page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mfsd2aem2(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A complementary DNA encoding Cre recombinase fused with 2 rox sequences flanking a mutant form of the ESR hormone-binding domain (ERT2) was inserted into the translational start site of the Mfsd2a gene. (J:278094)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mfsd2a (mouse)
Summary of all recombinase alleles driven by Mfsd2a.
 

Expression
In Mice Carrying this Mutation: 60 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mfsd2a Mutation:  41 strains or lines available
References
Original:  J:278094 Pu W, et al., Genetic Targeting of Organ-Specific Blood Vessels. Circ Res. 2018 Jun 22;123(1):86-99
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory