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Gene Expression Data
Assay Details
Assay
Reference: J:74155 Kagoshima M, et al., Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis. Genes Cells. 2001 Jun;6(6):559-71
Assay type: RNA in situ
MGI Accession ID: MGI:6361500
Gene symbol: Nrp2
Gene name: neuropilin 2
Probe: NP-2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lobar bronchus epithelium Present 1M
TS19: lung mesenchyme Present Diffuse 1M
Specimen 1N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Strong 1N
TS21: lung mesenchyme Weak Diffuse 1N
TS21: heart Absent 1N
TS21: rib cartilage condensation Strong 1N
TS21: vertebral cartilage condensation Strong 1N
TS21: esophagus Strong Regionally restricted 1N High expression in muscle layer around esophagus.
Specimen 1O: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Strong 1O Greater expression in epithelium. Higher expression in lobar bronchus rather than in terminal buds.
TS21: lung mesenchyme Weak Diffuse 1O
Specimen 2I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: bronchiole epithelium Strong 2I
TS23: lung mesenchyme Present Diffuse 2I
TS23: rib Strong 2I
TS23: vertebra Strong 2I
TS23: esophagus muscularis Strong 2I
Specimen 2J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: bronchiole epithelium Strong 2J
TS23: lung mesenchyme Present Diffuse 2J
Specimen 3I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: bronchiole epithelium Strong 3I
TS25: lung mesenchyme Present Diffuse 3I
TS25: rib Strong 3I
Specimen 3J: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: bronchiole epithelium Strong 3J
TS25: lung mesenchyme Present Diffuse 3J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory