About   Help   FAQ
Kitem2(cre)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Kitem2(cre)Bzsh
Name: KIT proto-oncogene receptor tyrosine kinase; endonuclease-mediated mutation 2, Bin Zhou
MGI ID: MGI:6361905
Synonyms: Kit-IRES-Cre
Gene: Kit  Location: Chr5:75735647-75817382 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance: Kitem2(cre)Bzsh page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Kitem2(cre)Bzsh expression driven by 1 gene
 
Mutation details: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. An internal ribosomal entery site (IRES) and complementary DNA encoding Cre recombinase replaced the translational stop codon and inserted in Kit gene. (J:278090)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Kit (mouse)
Summary of all recombinase alleles driven by Kit.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kit Mutation:  182 strains or lines available
References
Original:  J:278090 He L, et al., Reassessment of c-Kit(+) Cells for Cardiomyocyte Contribution in Adult Heart. Circulation. 2019 Jul 9;140(2):164-166
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory