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Ucp1em1(cre/ERT2)Wwz
Endonuclease-mediated Allele Detail
Summary
Symbol: Ucp1em1(cre/ERT2)Wwz
Name: uncoupling protein 1 (mitochondrial, proton carrier); endonuclease-mediated mutation 1, Wenwen Zeng
MGI ID: MGI:6363028
Synonyms: Ucp1CreERT2
Gene: Ucp1  Location: Chr8:84016981-84025081 bp, + strand  Genetic Position: Chr8, 39.65 cM
Alliance: Ucp1em1(cre/ERT2)Wwz page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Ucp1em1(cre/ERT2)Wwz expression driven by 1 gene
 
Mutation details: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. The IRES (internal ribosome entry site) followed by the CreERT2 sequence was inserted immediately after the stop codon of the Ucp1 coding region. (J:269774)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ucp1 (mouse)
Summary of all recombinase alleles driven by Ucp1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ucp1 Mutation:  51 strains or lines available
References
Original:  J:269774 Cao Y, et al., Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues. Mol Metab. 2018 Jun 7;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory