Ucp1<em1(cre/ERT2)Wwz> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6363028)

Ucp1^{em1(cre/ERT2)Wwz}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Ucp1^{em1(cre/ERT2)Wwz}
Name:	uncoupling protein 1 (mitochondrial, proton carrier); endonuclease-mediated mutation 1, Wenwen Zeng
MGI ID:	MGI:6363028
Synonyms:	Ucp1^CreERT2
Gene:	Ucp1 Location: Chr8:84016981-84025081 bp, + strand Genetic Position: Chr8, 39.65 cM
Alliance:	Ucp1^{em1(cre/ERT2)Wwz} page

Mutation
origin

Strain of Origin:

C57BL/6

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Ucp1^{em1(cre/ERT2)Wwz} expression driven by 1 gene

Mutation details: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. The IRES (internal ribosome entry site) followed by the CreERT2 sequence was inserted immediately after the stop codon of the Ucp1 coding region. (J:269774)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ucp1 (mouse) Summary of all recombinase alleles driven by Ucp1. Alliance mouse Ucp1 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ucp1 Mutation:	49 strains or lines available

References

Original:	J:269774 Cao Y, et al., Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues. Mol Metab. 2018 Jun 7;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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