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Wnt5atm1.1Homy
Targeted Allele Detail
Summary
Symbol: Wnt5atm1.1Homy
Name: wingless-type MMTV integration site family, member 5A; targeted mutation 1,1, Hiroaki Honda
MGI ID: MGI:6363418
Synonyms: Wnt5afl, Wnt5aflox
Gene: Wnt5a  Location: Chr14:28226707-28249405 bp, + strand  Genetic Position: Chr14, 16.8 cM
Alliance: Wnt5atm1.1Homy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:250197
Parent Cell Line:  KY1.1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation details: LoxP sites were inserted to flank exon 2, together with a Flp-recombinase target (Frt)-flanked neomycin resistance (Neo) gene cassette. The selection cassette was removed via FLP-mediated recombination. (J:250197)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt5a Mutation:  40 strains or lines available
References
Original:  J:250197 Sato A, et al., The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-gamma in colitis. Sci Rep. 2015 Jun 1;5:10536
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory