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Cdh5tm9Dvst
Targeted Allele Detail
Summary
Symbol: Cdh5tm9Dvst
Name: cadherin 5; targeted mutation 9, Dietmar Vestweber
MGI ID: MGI:6364620
Synonyms: VE-cadherin-EGFP, VE-cadherin-GFP
Gene: Cdh5  Location: Chr8:104828257-104871143 bp, + strand  Genetic Position: Chr8, 53.04 cM
Alliance: Cdh5tm9Dvst page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155181
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA GFP fusion protein is expressed from this allele via a cDNA construct knocked into the locus, thereby replacing the endogenous sequences of the gene. (J:155181)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh5 Mutation:  59 strains or lines available
Notes
This allele was generated from Cdh5tm1Dvst.
References
Original:  J:155181 Winderlich M, et al., VE-PTP controls blood vessel development by balancing Tie-2 activity. J Cell Biol. 2009 May 18;185(4):657-71
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory