Foxg1tm1.2Fsh
Targeted Allele Detail
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| Symbol: |
Foxg1tm1.2Fsh |
| Name: |
forkhead box G1; targeted mutation 1.2, Gordon Fishell |
| MGI ID: |
MGI:6368632 |
| Synonyms: |
FoxG1-Flpe |
| Gene: |
Foxg1 Location: Chr12:49429666-49433650 bp, + strand Genetic Position: Chr12, 21.78 cM
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| Alliance: |
Foxg1tm1.2Fsh page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:188355
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Recombinase) |
| Mutation: |
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Insertion
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Foxg1tm1.2Fsh expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: LoxP sites were inserted to flank the Foxg1 coding sequence. In addition, a Flpe gene was inserted 3' of the downstream loxP site, into the 3'end of the endogenous gene. An adjacent frt-flanked neomycin selection cassette was removed via Flp-mediated recombination. Cre-mediated recombination removed the Foxg1 coding sequences, leaving Flpe which is expressed from this locus.
(J:188355)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Foxg1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Foxg1 Mutation: |
29 strains or lines available
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| Original: |
J:188355 Miyoshi G, et al., Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron. 2012 Jun 21;74(6):1045-58 |
| All: |
1 reference(s) |
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Analysis Tools
