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Gene Expression Data
Assay Details
Assay
Reference: J:278327 Snider PL, et al., Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis. J Cardiovasc Dev Dis. 2019 Jun 22;6(2)
Assay type: RNA in situ
MGI Accession ID: MGI:6378757
Gene symbol: Cracd
Gene name: capping protein inhibiting regulator of actin
Probe: C530008M17Rik cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: neural fold Present 2A
TS12: thoracic segment of trunk Present Regionally restricted 2A Expression was detected in the second heart field/first branchial arch/outflow tract region where the primitive tubular heart attaches to the pharyngeal foregut.

Specimen 2B: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future hindbrain Present 2B
TS14: neural tube Present 2B
TS14: prosencephalon Present 2B
TS14: thoracic segment of trunk Present Regionally restricted 2B Expression was detected in the second heart field/first branchial arch/outflow tract region.
TS14: pericardium Present Regionally restricted 2B Expression was detected in the pericardial cavity adjacent to the outflow tract.

Specimen 2C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: brain Present 2C
TS22: dorsal root ganglion Present 2C
TS22: hindbrain Present 2C
TS22: spinal cord Present 2C

Specimen 2D: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: neural tube Present Widespread 2D Expression was detected throughout the neural tube, except in the floor plate.
TS16: neural tube floor plate Absent 2D

Specimen 2E: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: neural tube Present Widespread 2E Expression was detected throughout the neural tube, except in the floor plate.
TS18: neural tube floor plate Absent 2E
TS18: dorsal root ganglion Present 2E

Specimen 2F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Widespread 2F Expression was detected throughout the neural tube, except in the floor plate.
TS20: spinal cord floor plate Absent 2F
TS20: dorsal root ganglion Present 2F
TS20: sinus venosus Present 2F
TS20: sympathetic ganglion Present 2F

Specimen 2H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord mantle layer Present 2H Expression was at a reduced level compared to earlier stages.
TS22: spinal cord marginal layer Absent 2H
TS22: spinal cord roof plate Absent 2H
TS22: dorsal root ganglion Present 2H
TS22: sympathetic ganglion Present 2H
TS22: vagal nerve trunk Present 2H
TS22: lung Present Punctate 2H

Specimen 2I: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: spinal cord Weak Regionally restricted 2I Expression in the spinal cord was only in the mantle layer and was at a reduced level compared to earlier stages.
TS27: spinal cord marginal layer Absent 2I
TS27: dorsal root ganglion Present 2I
TS27: sympathetic ganglion Present 2I

Specimen 2K: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present 2K
TS27: hippocampus Present 2K
TS27: main olfactory bulb Present 2K

Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: glossopharyngeal preganglion Present 3A
TS15: neural tube Present 3A
TS15: secondary heart field Present 3A
TS15: sinus venosus Present 3A
TS15: pericardium Present Regionally restricted 3A Expression was detected in the dorsal pericardial wall that is contiguous with the outflow myocardium.

Specimen 3B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: outflow tract cardiac muscle Present Regionally restricted 3B Expression was detected in the outflow tract/secondary heart field region in the cardiomyocyte outer layer.
TS17: primitive ventricle Present Regionally restricted 3B Expression was detected in the right ventricle in the cardiomyocyte outer layer.
TS17: 2nd branchial arch mesenchyme Present 3B
TS17: trunk mesenchyme Present Regionally restricted 3B Expression was detected in mesenchyme between cardinal veins and dorsal aorta.

Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart atrium Present Regionally restricted 3D Expression was detected in the inflow region, in the walls of the atria.
TS17: foregut Present Regionally restricted 3D Expression was detected in the foregut endoderm.
TS17: common atrial chamber Present 3D
TS17: sinus venosus Present 3D

Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 3E
TS20: sinus venosus Present 3E
TS20: spinal cord Present 3E
TS20: sympathetic ganglion Present 3E

Specimen 3F: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: vena cava Present Regionally restricted 3F Expression was detected in the wall of the vena cava just before it enters the right atrium.

Specimen 3G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: atrium cardiac muscle Present Punctate 3G

Specimen 3H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: atrium cardiac muscle Present Punctate 3H
TS28: heart endothelium Absent 3H

Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary spermatocyte Strong 4A Very robust expression was detected in mitotic spermatogonia and meiotic primary spermatocytes Type A and B.
TS28: spermatogonium Strong 4A Very robust expression was detected in mitotic spermatogonia and meiotic primary spermatocytes Type A and B.
TS28: spermatid Absent 4A
TS28: spermatozoon Absent 4A

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary Absent

Specimen 4B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary spermatocyte Strong 4B Very robust expression was detected in mitotic spermatogonia and meiotic primary spermatocytes Type A and B.
TS28: spermatogonium Strong 4B Very robust expression was detected in mitotic spermatogonia and meiotic primary spermatocytes Type A and B.
TS28: spermatid Absent 4B
TS28: spermatozoon Absent 4B

Specimen 4D: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: intestine mesenchyme Present Punctate 4D Expression was detected in close apposition to the endoderm.

Specimen 4E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: crypt of lieberkuhn Present 4E

Specimen 4F: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: crypt of lieberkuhn Present 4F

Specimen 4H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: crypt of lieberkuhn Present 4H

Specimen 4I: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epidermis Weak 4I Limited expression was present in abdominal newborn skin epidermis.
TS27: hair root sheath Strong 4I
TS27: connective tissue Strong Regionally restricted 4I Robust expression was detected in connective tissue/bulge surrounding the hair follicles.
TS27: dermis Absent 4I
TS27: hair follicle dermal papilla Absent 4I

Specimen 4J: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: brown fat Present Punctate 4J Expression was punctate in brown adipose and fibrous septae.

Specimen 4K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: white fat Present 4K

Specimen 5C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: testis Present 5C

Specimen 5D: postnatal adult; Cracdem1(IMPC)J/Cracdem1(IMPC)J (more )
Structure Level Pattern Image Note
TS28: testis Weak 5D Homozygous mutant testis exhibits significantly reduced mRNA levels compared to controls, despite similar patterns of expression.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory