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Gene Expression Data
Assay Details
Assay
Reference: J:275243 Bosch PJ, et al., A critical role for the nuclear protein Akirin2 in the formation of mammalian muscle in vivo. Genesis. 2019 May;57(5):e23286
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379276
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4b Sim1-Cre;Aki2fl/+: embryonic day 10.5; Akirin2tm1Aki/Akirin2+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Sim1-cre)1Lowl/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Cre reporter.
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 4b Pecam1 tdTom Sim1-Cre;Aki2fl/+ , 4b Pecam1 Sim1-Cre;Aki2fl/+ Expression was detected in somite-derived endothelial cells.
Specimen 4b Sim1-Cre;Aki2fl/fl: embryonic day 10.5; Akirin2tm1Aki/Akirin2tm1Aki, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Sim1-cre)1Lowl/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Cre reporter.
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 4b Pecam1 tdTom Sim1-Cre;Aki2fl/fl , 4b Pecam1 Sim1-Cre;Aki2fl/fl The remaining tdTomato-positive cells in the mutant forelimb extensively co-express Pecam1 in somite-derived endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory