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Pvalbtm1(icre)Ksak
Targeted Allele Detail
Summary
Symbol: Pvalbtm1(icre)Ksak
Name: parvalbumin; targeted mutation 1, Kenji Sakimura
MGI ID: MGI:6382183
Synonyms: PV-Cre
Gene: Pvalb  Location: Chr15:78075314-78090600 bp, - strand  Genetic Position: Chr15, 36.93 cM, cytoband E
Alliance: Pvalbtm1(icre)Ksak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:279656
Parent Cell Line:  RENKA (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Epitope tag, Recombinase, Reporter)
Mutation:    Insertion
 
Pvalbtm1(icre)Ksak expression driven by 1 gene
 
Mutation details: The targeting construct with iCre-IRES-FLAG-EGFP cDNA followed by FRT flanked neomycin resistance cassette was placed just behind the translational initiation site of the Pvalb gene exon 2 in frame. (J:279656)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pvalb (mouse)
Summary of all recombinase alleles driven by Pvalb.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pvalb Mutation:  29 strains or lines available
References
Original:  J:279656 Inoue M, et al., Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics. Cell. 2019 May 16;177(5):1346-1360.e24
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory