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Gene Expression Data
Assay Details
Assay
Reference: J:272234 Chowdhury B, et al., Hyaluronidase 2 Deficiency Causes Increased Mesenchymal Cells, Congenital Heart Defects, and Heart Failure. Circ Cardiovasc Genet. 2017 Jan;10(1)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6382772
Gene symbol: Vim
Gene name: vimentin
Antibody: anti-vimentin (ab45939)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 3J: postnatal month 6; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Note: acute: severely affected
Structure Level Pattern Image Note
TS28: heart atrium Present 3J Increased expression in the mesenchymal cells, compared with the control and the chronic.
TS28: heart mesentery Present 3J Increased expression in the mesenchymal cells, compared with the control and the chronic.

Specimen 3K: postnatal month 6; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Note: chronic: less severely affected
Structure Level Pattern Image Note
TS28: heart atrium Present 3K Increased expression in the mesenchymal cells, compared with the control.
TS28: heart mesentery Present 3K Increased expression in the mesenchymal cells, compared with the control.

Specimen 3L: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: heart atrium Present 3L Expression in the mesenchymal cells.
TS28: heart mesentery Present 3L Expression in the mesenchymal cells.

Specimen 4E: embryonic day 18.5; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Structure Level Pattern Image Note
TS26: heart atrium Present 4E Increased expression in the mesenchymal cells, compared with the control.
TS26: heart mesentery Present 4E Increased expression in the mesenchymal cells, compared with the control.

Specimen 4F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: heart atrium Present 4F Expression in the mesenchymal cells.
TS26: heart mesentery Present 4F Expression in the mesenchymal cells.

Specimen 6E: embryonic day 14.5; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Structure Level Pattern Image Note
TS22: heart mesentery Present 6E Increased expression in the mesenchymal cells, compared with the control.

Specimen 6F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart mesentery Present 6F

Specimen S3J: postnatal month 6; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Note: acute: severely affected
Structure Level Pattern Image Note
TS28: heart mesentery Present S3J Increased expression in the mesenchymal cells, compared with the control.
TS28: heart ventricle Present S3J Increased expression in the mesenchymal cells, compared with the control.

Specimen S3K: postnatal month 6; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Note: chronic: less severely affected
Structure Level Pattern Image Note
TS28: heart mesentery Present S3K Increased expression in the mesenchymal cells, compared with the control and the acute.
TS28: heart ventricle Present S3K Increased expression in the mesenchymal cells, compared with the control and the acute.

Specimen S3L: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: heart mesentery Present S3L Expression in the mesenchymal cells.
TS28: heart ventricle Present S3L Expression in the mesenchymal cells.

Specimen not shown: embryonic day 18.5 (more )
Note: Quantified in Fig. 4H.
Structure Level Pattern Image Note
TS26: heart mesentery Present Expression in the mesenchymal cells.
TS26: heart ventricle Present Expression in the mesenchymal cells.

Specimen not shown: embryonic day 18.5; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Note: Quantified in Fig. 4H.
Structure Level Pattern Image Note
TS26: heart mesentery Present Increased expression in the mesenchymal cells, compared with the control.
TS26: heart ventricle Present Increased expression in the mesenchymal cells, compared with the control.

Specimen not shown: embryonic day 14.5 (more )
Note: Quantified in Fig. 6I/J.
Structure Level Pattern Image Note
TS22: heart atrium Present
TS22: heart mesentery Present
TS22: heart ventricle Present

Specimen not shown: embryonic day 14.5; Hyal2tm1.1Bfla/Hyal2tm1.1Bfla (more )
Note: Quantified in Fig. 6I/J.
Structure Level Pattern Image Note
TS22: heart atrium Present Increased expression in the mesenchymal cells, compared with the control.
TS22: heart mesentery Present Increased expression in the mesenchymal cells, compared with the control.
TS22: heart ventricle Present Increased expression in the mesenchymal cells, compared with the control.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory